Tamoxifen Nolvadex 10 mg - 50 tab

In bodybuilding, Nolvadex (Tamoxifen Citrate) is used as both an anabolic steroid cycle ancillary drug and as recovery or as a post anabolic steroid cycle therapy drug.

Nolvadex is an oral anti-estrogen/estrogen antagonist prescription drug. Nolvadex is commonly referred to as an anti-estrogen, but technically it is more of an estrogen antagonist. An estrogen antagonist has a unique way of preventing estrogen activity. What it does is to compete with estrogen at the receptor sites, occupying it so that estrogen cannot bind with it.

Nolvadex is an anticancer drug which is reportedly effective in treating breast cancer, particularly the kind that is induced by estrogen. Its other therapeutic uses include reduction of the risk of invasive breast cancer following surgery and radiation therapy for ductal carcinoma in situ. Nolvadex is also used as preventive drug. It is prescribed in women who are at high risk of developing breast cancer (genetic disposition).

Why is there a need for Nolvadex

During a steroid cycle, Nolvadex is used by bodybuilders who are sensitive to estrogen buildup. Estrogen buildup can lead to many concerns, foremost of these is the occurrence of gynecomastia (growth of breast tissues in men) and subcutaneous fat and water retention. 

During PCT, Nolvadex is effective in averting the dreaded effect when coming off a steroid cycle – the post-cycle crash. This is basically losing what you have gained when you’re on a cycle. Bodybuilders, in general, use Nolvadex to block this from taking place. 

Here’s the scenario. When a bodybuilder is taking anabolic steroids, the body ceases its production of androgens. When he stops taking them, the body does not immediately resume its normal production of these hormones, resulting to depressed androgen level. When this happens the body compensates by overproducing estrogen. The excess estrogen, in turn, results to can increase the production of SHBG and blocks testosterone-receptor sites. SHBG or sex hormone-binding globulin is a glycoprotein that binds to sex hormones, including testosterone. And so, if there’s an increase in the amount of SHBG in the system it translates to lesser amount of free or unbound testosterone. This means there are two mechanisms by which excess estrogen interferes with the normalization of androgen level in the body.